ChemInform Abstract: Bromotriphenylphosphonium Salt Promoted One-Pot Cyclization to 2-Fluoroalkyl-Substituted Indoles

Autor:	Wei-gui Ni, Qing-wen Ma, Tai-feng Zhang, Zeng-xue Wang
Rok vydání:	2015
Předmět:	Indole test chemistry.chemical_classification chemistry.chemical_compound chemistry education Salt (chemistry) Organic chemistry General Medicine Ring (chemistry) Triethylamine Toluene
Zdroj:	ChemInform. 46
ISSN:	0931-7597
DOI:	10.1002/chin.201519155
Popis:	2-Fluoroalkyl-substituted indoles were prepared in moderate to excellent yields through bromotriphenylphosphonium salt promoted ring formation with fluorine-containing carboxylic acids in the presence of triethylamine in toluene at reflux temperature. A range of 2-fluoroalkyl-substituted indole derivatives can be conveniently prepared.
Databáze:	OpenAIRE
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