Blood glucose and insulin levels during epidural anaesthesia in children receiving dextrose-free solutions

Autor: Louise Gouyet, I. Murat, M.C. Dubois
Rok vydání: 1994
Předmět:
Zdroj: Pediatric Anesthesia. 4:307-311
ISSN: 1460-9592
1155-5645
DOI: 10.1111/j.1460-9592.1994.tb00393.x
Popis: Summary This study was designed to evaluate the hyperglycaemic response to surgery in two groups of children undergoing minor surgical procedures and receiving dextrose-free solutions during the perioperative period. Twenty-four unpremedicated children of less than eight years of age were randomly assigned to receive either general anaesthesia using halothane, vecuronium and narcotics (GA group, n= 12) or general anaesthesia (halothane, vecuronium) combined with caudal anaesthesia (RA group, n= 12). In both groups blood glucose and insulin concentrations were measured during inhalational induction (T0), at the end of surgery (T1) and 30, 60, 120 min after surgery (T2, T3, T4). A significant hyperglycaemic response to surgery was observed in the GA group, while no changes in blood glucose were observed in the RA group. The maximal blood glucose value was observed 30 min after completion of surgery. Insulin changes followed closely changes in blood glucose values. This study demonstrates that epidural anaesthesia was effective in reducing the hyperglycaemic response to surgery in children scheduled for minor surgical procedures. The lack of increase in blood glucose values under epidural anaesthesia suggests that blood glucose levels should be monitored during the perioperative period, especially after a prolonged fasting time and when oral intake might be delayed.
Databáze: OpenAIRE
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