Starved human fibroblasts secrete acidic proteins inducing post re-feeding proliferation andin vitrocell migration: A potential tool for wound healing

Autor: Sadegh Fattahi, Ali Bijani, Monireh Golpour, Zeinab Abedian, Hamidreza Vaziri, Hamid Reza Khorasani, Abbas Hadipoor, Haleh Akhavan Niaki, Amrollah Mostafazadeh, Hadi Parsian, Abbas Mosapour, Gholam Reza Ahangarian
Rok vydání: 2014
Předmět:
Zdroj: Biology of the Cell. 106:139-150
ISSN: 0248-4900
Popis: Background Information There are several reports indicating that starved fibroblasts show higher proliferation rates when re-fed with foetal bovine serum. We have evidence demonstrating that this phenomenon is related to secretory proteins which may be beneficial to wound healing. Results After re-feeding, 16 and 72 h serum-starved fibroblasts showed the highest and lowest proliferation rates, 1.59 and 0.51-fold difference compared to the non-starved control, respectively (P
Databáze: OpenAIRE