The remote effects of radiation after hypofractionated irradiation with protons of Ehrlich ascites carcinoma in mice
| Autor: | O. M. Rozanova, N. S. Strelnikova, A. E. Shemyakov, V. E. Balakin, Zaichkina Si, Smirnova En, S. S. Sorokina, S. P. Romanchenko |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Chemistry business.industry Biophysics Planning target volume Scanning beam Radiation Ehrlich ascites carcinoma Gross tumor volume Pencil (optics) 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Total dose Irradiation Nuclear medicine business |
| Zdroj: | Biophysics. 62:138-142 |
| ISSN: | 1555-6654 0006-3509 |
| DOI: | 10.1134/s0006350917010043 |
| Popis: | This work focuses on the study of remote effects (duration of remission, recurrence rate, and average lifespan) in mice with Ehrlich ascites carcinoma exposed to oligofractionated irradiation with a pencil scanning beam of protons depending on the volume of the tissue being irradiated and the interval between dose fractions. The results show higher antitumor efficacy and a considerable increase in the average life span of mice after hypofractionated irradiation with a pencil scanning beam of protons at a total dose of 60 Gy of the gross tumor volume compared with the planning target volume. |
| Databáze: | OpenAIRE |
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