In-vitro-Untersuchungen zur gepulsten Laserangioplastie in flüssigem und gasförmigem Medium

Autor: R Birngruber, M. Zwaan, R. Engelhardt, A Vogel, U. Behnle, W. Kloess, Hans-Dieter Weiss
Rok vydání: 1996
Předmět:
Zdroj: RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 164:68-71
ISSN: 1438-9010
1438-9029
Popis: Purpose In a vascular model the mechanisms of a pulsed dye laser working in a liquid and a gaseous environment was tested and documented by means of a high-speed camera. Methods The pulse application (630 nm wavelength) on a target of calcified arterial plaque material was detected at intervals of 20 microseconds up to 800 microseconds total time. Results In water the laser beam created a cavitation bubble which expanded from 0 to 450 microseconds from a radius 0 to 3 mm and collapsed afterwards. The average expansion velocity of the bubble was 80 m/s in the first 20 microseconds and the resulting velocity of the tube model wall was 10 m/s. Compared with gaseous atmosphere there was no bubble and consecutively no wall stress. Conclusion It is obvious that laser angioplasty causes wall stress and destruction of different vascular layers. This might be the initial stimulation for restenosis. In gaseous atmosphere laser angioplasty should be more protective.
Databáze: OpenAIRE