Characterization and in vitro cytotoxic assessment of zinc oxide nano-particles in human epidermoid carcinoma cells
| Autor: | Qamar Zia, Arshad, Asif Jafri, Mohd. Farhan Khan, Md. Manzar Alam, Bader A. Alshehri, Saeed Banawas, Ali Mohammadi, Akhter H. Ansari, Sahabjada Siddiqui, Ejaz Ahmad, Alaa Baazeem, Azfar Jamal, Fayez Althobaiti |
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| Rok vydání: | 2021 |
| Předmět: |
Chemistry
Process Chemistry and Technology Nanoparticle chemistry.chemical_element Human skin 02 engineering and technology Zinc 010501 environmental sciences 021001 nanoscience & nanotechnology 01 natural sciences Pollution In vitro Crystallinity Epidermoid carcinoma Apoptosis Chemical Engineering (miscellaneous) Cytotoxic T cell 0210 nano-technology Waste Management and Disposal 0105 earth and related environmental sciences Nuclear chemistry |
| Zdroj: | Journal of Environmental Chemical Engineering. 9:105636 |
| ISSN: | 2213-3437 |
| Popis: | The study was designed to evaluate the effect of varying concentrations of ion-carriers on the synthesis of zinc oxide nano-particles (ZONs). We also evaluated the anti-proliferative activity, morphological changes, ROS generation, nuclear apoptosis and caspase-3 activity of two ZON samples in human skin cancer cell line A431. The XRD analysis of both samples confirmed the crystallinity and pure nature of ZONs. SEM analysis showed spider chrysanthemum-like shape, while the TEM data determined the diameter size of nanostructures as 40 nm (ZON-1) and |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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