Serum paraoxonase – Marker of alcoholic liver cirrhosis

Autor:	J. Rama Rao, Naazia Arifuddin, V. Uma Lakshmi, Ch. Kiranmai, B. Jyotchna Devi
Rok vydání:	2020
Předmět:	medicine.medical_specialty Alcoholic liver disease Cirrhosis biology Clusterin medicine.diagnostic_test Paraoxonase medicine.disease_cause medicine.disease Gastroenterology Internal medicine medicine biology.protein Biomarker (medicine) Apolipoprotein A1 Liver function tests Oxidative stress
Zdroj:	International Journal of Clinical Biochemistry and Research. 5:513-516
ISSN:	2394-6377 2394-6369
Popis:	Serum Paraoxonase is an esterase, along with Apolipoprotein A1 and Clusterin (Apolipoprotein J), PON 1 is associated with HDL. This study was done to assess the significance of serum Paraoxonase as an biomarker along with standard liver function tests in evaluating alcoholic cirrhosis. Serum Paraoxonase levels was estimated in 30 patients diagnosed with alcoholic cirrhosis and 30 healthy blood donors. Paraoxonase levels were significantly lower in cases as compared with controls (P Conclusion : Serum Paraoxonase is sensitive marker for patients with alcoholic liver disease and oxidative stress and should be included as an additional parameter along with the other parameters in liver function tests. Keywords: Alcoholic cirrhosis, Antioxidant, Paraoxonase, Liver function tests.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f3e0ae2bcdfe8d69aa1aa31370dbcdd7 https://doi.org/10.18231/2394-6377.2018.0109 Zobrazit plný text záznamu