Palladium-Catalyzed Dehydrogenation Coupling–Cyclization Reactions of Acetylenic Acids with Iodonium Ylides for the Synthesis of 2(5H)-Furanones

Autor:	Xiao Hongbo, Bo Cai, Han-Zhou Sun, Pi Shaofeng, Wen-Guang Li
Rok vydání:	2015
Předmět:	chemistry.chemical_classification Coupling (electronics) chemistry Base (chemistry) Cascade reaction Organic Chemistry chemistry.chemical_element Organic chemistry Dehydrogenation Medicinal chemistry Palladium Catalysis
Zdroj:	Synlett. 27:794-798
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0035-1560554
Popis:	A new route for the synthesis of 2(5H)-furanones is presented via Pd(PPh3)4-catalyzed cascade reaction of acetlenic acids with iodonium ylides using K2CO3 as the base. The cascade proceeds through dehydrogenation coupling and cyclization under mild conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f3c46465ae6bb3102ab095d9b8ca4ce0 https://doi.org/10.1055/s-0035-1560554 Zobrazit plný text záznamu