Molecular-Level Dengue Fever Diagnostics: Developing a Combination of RT-LAMP and Paper-Based Devices

Autor: Shih-Chun Yang, Jiann-Hwa Chen, Shih-Jie Lo, Da-Jeng Yao, Chao-Min Cheng
Rok vydání: 2012
Předmět:
Zdroj: IEEE Nanotechnology Magazine. 6:26-30
ISSN: 1932-4510
Popis: This article describes the development of an inexpensive but robust and easy-to-use point-of-care diagnostic device that can be used for the detection of dengue fever at the molecular level (i.e., the detection of dengue virus using a piece of paper). To date, the clinical diagnosis of dengue fever mainly relies on enzyme-linked immunosorbent assay-based examinations for a specific antigen. However, protein-based diagnostics are used at a relatively late stage of the infection, and there is a need to develop a simple and low-cost diagnostic device for the detection of dengue fever at the early stages of the infection.
Databáze: OpenAIRE