Expression of MxA Protein in Triple Negative Breast Cancer and its Relationship with Prognosis

Autor:	Hong Chen, Qiushuang Ma, Jinku Zhang, Jinmei Li, Jirui Sun
Rok vydání:	2020
Předmět:	Oncology medicine.medical_specialty Breast tissue biology business.industry Distant metastasis General Medicine medicine.disease Blot Breast cancer Internal medicine biology.protein medicine Overall survival Mxa protein Protein A business Triple-negative breast cancer
Zdroj:	Proceedings of Anticancer Research. 4
ISSN:	2208-3553 2208-3545
DOI:	10.26689/par.v4i3.1257
Popis:	Objective: To explore the expression of human myxovirus resistance protein A (MxA) in triple negative breast cancer (TNBC) and its relationship with prognosis. Methods: 144 cases of TNBC confirmed by pathology before or after surgery from January 2014 to January 2017 in the First Central Hospital of Baoding City were retrospectively collected. Western blotting was used to detect the expression of MxA protein in TNBC and adjacent breast tissues. According to the expression of MxA protein, 144 TNBC patients were divided into low MxA protein expression group (n = 91) and MxA protein high expression group (n = 53) for subsequent comparison of prognosis of patients in between these two groups. Results: The expression of MxA protein in TNBC tissue was lower than that of adjacent breast tissue, and the difference was statistically significant (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f115fbf2230fd622817281d2d78e0d05 https://doi.org/10.26689/par.v4i3.1257 Zobrazit plný text záznamu