Rapidly Progressive Homonymous Hemianopia in the Heidenhain Variant of Creutzfeldt-Jakob Disease
| Autor: | Gerard L. Hershewe, Eric K. Chin, John L. Keltner |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pathology
medicine.medical_specialty Ataxia medicine.diagnostic_test business.industry Cortical blindness Magnetic resonance imaging medicine.disease eye diseases nervous system diseases Ophthalmology Atrophy Degenerative disease mental disorders medicine Neurology (clinical) medicine.symptom business Myoclonus Retinal thinning Emission computed tomography |
| Zdroj: | Neuro-Ophthalmology. 36:54-58 |
| ISSN: | 1744-506X 0165-8107 |
| Popis: | Creutzfeldt-Jakob disease is a rare degenerative disease of the brain characterized by rapid irreversible neurological decline. The Heidenhain variant describes any case of Creutzfeldt-Jakob disease in which visual symptoms predominate in the early stages. The authors report a 63-year-old female who had rapidly progressive bilateral visual field loss since 2 months prior to evaluation. Over the following 2 weeks, the patient developed rapidly progressive visual changes and eventually died. Her case has several unusual features: (1) lack of neurological deficits classically seen with Creutzfeldt-Jakob disease such as myoclonus and ataxia; (2) rapid progression of a clearly documented consecutive homonymous hemianopia over less than 2.5 months from onset of symptoms to death; (3) early symmetric temporal atrophy of the optic nerves and paracentral retinal thinning with optical coherence tomography imaging; (4) negative single-photon emission computed tomography imaging; and (5) negative magnetic resonance i... |
| Databáze: | OpenAIRE |
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