Autor: |
Loredana Cappellacci, Mario Grifantini, Barry M. Goldstein, R. Moraca, Giuseppe Nocentini, G. Abu Sheikha, Palmarisa Franchetti, L. Messini |
Rok vydání: |
1995 |
Předmět: |
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Zdroj: |
Nucleosides, Nucleotides and Nucleic Acids. 14:637-640 |
ISSN: |
1525-7770 |
DOI: |
10.1080/15257779508012440 |
Popis: |
The syntheses and antitumor activity of 2-β-D-ribofuranosylfuran-4-carboxamide (furanfurin) and 2-β-D-ribofuranosylthiophene-4-carboxamide (thiophenfurin) are reported. The X-ray structure of ethyl 2-β-D-ribofuranosylthiophene-4-carboxylate, precursor of thiophenfurin, is also presented. Only thiophenfurin showed activity as an antitumor agent both in vitro and in vivo. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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