Protective effect of the ketogenic diet in Scn1a mutant mice

Autor:	Karin Borges, Stacey B. B. Dutton, Franck Kalume, Nikki T. Sawyer, William A. Catterall, Patricia Jumbo-Lucioni, Andrew Escayg
Rok vydání:	2011
Předmět:	Epithelial sodium channel business.industry medicine.medical_treatment Mutant Flurothyl Convulsants Pharmacology medicine.disease Epilepsy Neurology Dravet syndrome medicine Neurology (clinical) medicine.symptom business Weight gain Ketogenic diet
Zdroj:	Epilepsia. 52:2050-2056
ISSN:	0013-9580
DOI:	10.1111/j.1528-1167.2011.03211.x
Popis:	Purpose We evaluated the ability of the ketogenic diet (KD) to improve thresholds to flurothyl-induced seizures in two mouse lines with Scn1a mutations: one that models Dravet syndrome (DS) and another that models genetic (generalized) epilepsy with febrile seizures plus (GEFS+).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::eec47a693d8bb99f718a32f5d2b847f2 https://doi.org/10.1111/j.1528-1167.2011.03211.x Zobrazit plný text záznamu Plný text