Cognitive-behavioral therapy for psychogenic nonepileptic seizures: A pilot RCT
| Autor: | Trudie Chalder, Laura H. Goldstein, Mizanur Khondoker, C. Chigwedere, John Moriarty, John Dc Mellers, Brian Toone |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment medicine.disease law.invention Cognitive behavioral therapy Epilepsy Randomized controlled trial law Internal medicine Psychogenic non-epileptic seizures cardiovascular system medicine Cognitive therapy Functional neurological symptom disorder Physical therapy Psychogenic disease Neurology (clinical) Young adult Psychology |
| Zdroj: | Neurology. 74:1986-1994 |
| ISSN: | 1526-632X 0028-3878 |
| DOI: | 10.1212/wnl.0b013e3181e39658 |
| Popis: | Objective: To compare cognitive-behavioral therapy (CBT) and standard medical care (SMC) as treatments for psychogenic nonepileptic seizures (PNES). Methods: Our randomized controlled trial (RCT) compared CBT with SMC in an outpatient neuropsychiatric setting. Sixty-six PNES patients were randomized to either CBT (plus SMC) or SMC alone, scheduled to occur over 4 months. PNES diagnosis was established by video-EEG telemetry for most patients. Exclusion criteria included comorbid history of epilepsy, Results: In an intention-to-treat analysis, seizure reduction following CBT was superior at treatment end (group × time interaction p Conclusions: Our findings suggest that cognitive-behavioral therapy is more effective than standard medical care alone in reducing seizure frequency in PNES patients. Classification of evidence: This study provides Class III evidence that CBT in addition to SMC, as compared to SMC alone, significantly reduces seizure frequency in patients with PNES (change in median monthly seizure frequency: baseline to 6 months follow-up, CBT group, 12 to 1.5; SMC alone group, 8 to 5). |
| Databáze: | OpenAIRE |
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