Convective Dialysis Reduces Mortality Risk: Results From a Large Observational, Population-Based Analysis
| Autor: | Francesco La Torre, Valeria Cernaro, Gaetano Montalto, Domenico Santoro, Antonio Lacquaniti, Luca Visconti, Giovanni Tripepi, Domenica Cimadoro, Giuseppe Costantino, Adolfo Romeo, Michele Buemi |
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| Rok vydání: | 2018 |
| Předmět: |
Nephrology
medicine.medical_specialty business.industry medicine.medical_treatment Mortality rate Hazard ratio 030232 urology & nephrology Retrospective cohort study Hematology 030204 cardiovascular system & hematology Transplantation 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Renal replacement therapy business Dialysis Cohort study |
| Zdroj: | Therapeutic Apheresis and Dialysis. 22:457-468 |
| ISSN: | 1744-9979 |
| DOI: | 10.1111/1744-9987.12684 |
| Popis: | According to many studies, extracorporeal dialysis with convective methods is associated with better clinical outcomes and a survival benefit compared to diffusive techniques. However, there is no full agreement on the actual superiority of this kind of renal replacement therapy on hard end-points such as mortality. We performed a retrospective epidemiological cohort study to provide "real-world" evidence on the impact of convective and non-convective dialysis techniques on all-cause and cardiac mortality and biochemical outcomes among dialysis patients in Sicily, the southernmost region of Italy. Data of all incident adult patients (N = 6529) who have started chronic extracorporeal dialysis over the period 2009-2015 were retrieved from the Sicilian Registry of Nephrology, Dialysis and Transplantation. There were 1558 patients receiving convective techniques (23.86%). Overall mortality rate was 45.21% with a significant difference between convective (31.39%) and non-convective (49.55%) groups (P |
| Databáze: | OpenAIRE |
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