THE FACTOR STRUCTURE OF THE PATIENT HEALTH QUESTIONNAIRE-9 IN STROKE: A COMPARISON WITH A NON-STROKE POPULATION

Autor: J.J. Blake, T. Munyombwe, F. Fischer, T.J Quinn, C.M. Van der Feltz-Cornelis, J.M. De Man-van Ginkel, I.S. Santos, H.J. Jeon, S. Köhler, M.T. Schram, C.D.A. Stehouwer, Jianli Wang, H.F. Levin-Aspenson, M.A. Whooley, S.E Hobfoll, S.B. Patten, A. Simning, F. Gracey, N.M. Broomfield
Rok vydání: 2023
DOI: 10.1101/2023.03.24.23287728
Popis: BackgroundThere are concerns that the measurement of depression by the Patient Health Questionnaire-9 (PHQ-9), a self-report screening questionnaire, is biased by comorbid stroke sequelae. We, therefore, aimed to investigate these concerns in stroke, benchmarked against a non-stroke comparison sample, using factor analysis.MethodsThe secondary data sample constituted 787 stroke and 12,016 non-stroke participants, in a cross-sectional design. A subsample of 1,574 non-stroke participants was selected via propensity score matching. Dimensionality was assessed by comparing fit statistics of one-factor, two-factor, and bi-factor models. Between-group differences in factor structure were identified using measurement invariance.ResultsA two-factor model, consisting of somatic and cognitive-affect factors, had a superior fit to a unidimensional model (CFI = .984 versus CFI =.974, ps d=.434).ConclusionsThe findings suggest that the PHQ-9 measures a single latent factor in stroke. However, the presence of non-invariant intercepts means that PHQ-9 total scores may be disproportionately influenced by fatigue in post-stroke vs. non-stroke patients and that total scores are incomparable between groups.
Databáze: OpenAIRE