Calciphylaxie non urémique iatrogène : une nouvelle observation
| Autor: | Michèle Sanchez, Hugo Tristani, Soumaya Hamich, Brigitte Lagrange, Martin Mazereeuw, Olivier Lavelle, Julien Rakotoson |
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| Rok vydání: | 2020 |
| Předmět: |
Calciphylaxis
medicine.medical_specialty business.industry medicine.medical_treatment Rheopheresis 030232 urology & nephrology Sodium thiosulfate medicine.disease Thrombosis Dermatology 03 medical and health sciences Normal renal function chemistry.chemical_compound 0302 clinical medicine chemistry Nephrology medicine In patient business Dialysis Calcification |
| Zdroj: | Néphrologie & Thérapeutique. 16:431-436 |
| ISSN: | 1769-7255 |
| Popis: | Calciphylaxis is a rare and severe condition, characterized by calcification and thrombosis of small vessels, mainly affecting the skin. It is most often described in patients with end-stage renal disease on dialysis. Rarer cases of non-uremic calciphylaxis are reported. The prognosis is grim and the treatment is not well codified. Sodium thiosulfate has been used for more than a decade in the treatment of uremic calciphylaxis and has been shown to be effective. Its use in non-uremic cases has been reported in a few rare observations. Rheopheresis is a technique very recently used as an adjuvant treatment in uremic calciphylaxis. We describe a case of non-uremic calciphylaxis in a patient with normal renal function and with calcium supplementation. Sodium thiosulfate was introduced, then discontinued due to the patient's poor tolerance for this treatment. Rheopheresis was then used and allowed the acceleration of healing process and a significant reduction in pain. These two treatments are promising, larger studies are needed to establish their effectiveness in non-uremic calciphylaxis. |
| Databáze: | OpenAIRE |
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