Multi-wavelength calibration: Determination of trace toxic elements in medicine plants by ICP OES
| Autor: | A M B Goncalves, Valter Aragão do Nascimento, Elaine Silva de Pádua Melo, Lincoln Carlos Silva de Oliveira, Igor Domingos de Souza, Ana Carla Gomes Rosa, Daniel A. Gonçalves |
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| Rok vydání: | 2019 |
| Předmět: |
Analyte
Chromatography Materials science 010401 analytical chemistry Relative standard deviation chemistry.chemical_element Multi wavelength 02 engineering and technology Standard solution 021001 nanoscience & nanotechnology 01 natural sciences World health 0104 chemical sciences Analytical Chemistry chemistry Inductively coupled plasma atomic emission spectroscopy Calibration 0210 nano-technology Spectroscopy Arsenic |
| Zdroj: | Microchemical Journal. 146:381-386 |
| ISSN: | 0026-265X |
| Popis: | In the present work a promising method for elemental impurities quantification, such as As, Cd, Cr, Cu, Ni and Pb in medicinal plants, called Multi-Wavelength Calibration - MWC, is shown. Calibration and quantification are performed with only two solutions. The first solution contains sample and a standard solution of known concentration of each analyte (1:1 v−1), and the second solution contains sample and a blank sample solution (1:1 v−1). The method was validated using addition and recovery tests, and content quantification of each analyte in SRM 1570a and SRM 1575a. The recoveries obtained were between 96.90–99.90% and relative standard deviation of 1.40%. The results obtained in the quantification of SRMs demonstrate excellent method accuracy. The levels of elemental impurities present in medicinal plants had concentrations above that allowed for As, Cr, Cu, Ni and Pb, and higher concentrations for arsenic, when compared to the maximum limits allowed by the Brazilian Pharmaceutical, World Health Organization, National Sanitation Foundation International and European Medicines Agency. The results demonstrated that the MWC is a fast, accurate and highly sensitive alternative to the methods used by the main regulatory agencies to determine elemental impurities in medicinal and phytotherapeutic plants. |
| Databáze: | OpenAIRE |
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