Diisopropyl azodicarboxylate mediated selective dehydrogenation of 2-amino-3-cyano 4 H -chromenes

Autor:	Debanjan Guin, Mohini Mourya, M. P. Dobhal, Yogesh Joshi, H. L. Sharma, Ashok K. Basak
Rok vydání:	2017
Předmět:	chemistry.chemical_compound chemistry 010405 organic chemistry Diisopropyl azodicarboxylate Organic Chemistry Drug Discovery Organic chemistry Dehydrogenation 010402 general chemistry Coumarin 01 natural sciences Biochemistry 0104 chemical sciences
Zdroj:	Tetrahedron Letters. 58:1727-1732
ISSN:	0040-4039
Popis:	Selective dehydrogenation of 2-amino-3-cyano 4H-chromenes to the corresponding 2-iminochromenes mediated by diisopropyl azodicarboxylate under neutral conditions is reported. The dehydrogenation reaction is compatible with phenolic hydroxyl group and generates iminochromene in high yields. The methodology provides an easy access to coumarin and N-tosyl 2-amino-3-cyano-4-aryl 4H-chromenes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ec7b3fb2462a5db5bcbed449619425de https://doi.org/10.1016/j.tetlet.2017.03.049 Zobrazit plný text záznamu Full Text from ScienceDirect