Oligodeoxyguanylates: A case of self-assembly leading to lyotropic liquid crystals

Autor:	Anna Garbesi, Gian Piero Spada, Paolo Mariani, Giovanni Gottarelli
Rok vydání:	1993
Předmět:	Circular dichroism General Chemical Engineering Hexagonal phase Guanosine General Chemistry Small-angle neutron scattering chemistry.chemical_compound Crystallography chemistry Liquid crystal Lyotropic liquid crystal Phase (matter) X-ray crystallography sense organs
Zdroj:	Pure and Applied Chemistry. 65:641-646
ISSN:	1365-3075 0033-4545
DOI:	10.1351/pac199365040641
Popis:	The guanosine derivatives d(Gp) 1-5G, dissolved in water, give rise to choles- teric and hexagonal mesophases. The results of X-ray Diffraction, Optical Microscopy, Circular Dichroism and Small Angle Neutron Scattering measurements indicate that the building block of the liquid-crystalline phases is a chiral rod, composed of a stacked array of Hoogsteen-bonded guanosine tetramers. The concentration at which the cholesteric phase appears increases with the oligomerisation degree, a pattern that seems to be related to the change of the ratio of negative charge/guanine units along the series.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ebf5448a64791819752bf3581b7d0511 https://doi.org/10.1351/pac199365040641 Zobrazit plný text záznamu