UV-Patterning of Anti-Biofouling Zwitterionic Copolymer Layer with an Aromatic Anchor Group
| Autor: | Tadashi Nakaji-Hirabayashi, Takahiro Kishioka, Ken-ichi Tokuwa, Lifu Li, Yuki Usui, Hiromi Kitano, Kohji Ohno |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Materials science 010304 chemical physics Polymers and Plastics biology General Chemical Engineering Organic Chemistry Substrate (chemistry) 02 engineering and technology Polymer 021001 nanoscience & nanotechnology 01 natural sciences Adsorption Chemical engineering chemistry 0103 physical sciences Materials Chemistry biology.protein Copolymer Organic chemistry Wafer Bovine serum albumin 0210 nano-technology Layer (electronics) Protein adsorption |
| Zdroj: | Macromolecular Materials and Engineering. 302:1600374 |
| ISSN: | 1438-7492 |
| DOI: | 10.1002/mame.201600374 |
| Popis: | A thin layer (around 2 nm in thickness) composed of a random copolymer of zwitterionic carboxymethyl betaine (CMB) and p-trimethoxysilylstyrene (STMS) (9:1) is constructed on a glass substrate or a silicon wafer. The copolymer layer is highly resistant against nonspecific adsorption of bovine serum albumin (BSA). However, on UV irradiation at 193 nm, the layer becomes hydrophobic and BSA is significantly adsorbed on the substrate. Upon UV irradiation through a photomask, a patterning of the fluorophore-labeled protein with a resolution of about 1 µm can be clearly observed. On the other hand, the copolymer layer of CMB and 3-methacryloxypropyltrimethoxysilane (MPTMS) (9:1) without an aromatic group exhibit less distinct pattern. Further, the poly(CMB-r-STMS) layer decomposes more quickly compared with the poly(CMB-r-MPTMS) layer at low irradiation dose. The zwitterionic polymer layer with an aromatic anchor group will be used at the modification of substrates applicable to sensing devices. |
| Databáze: | OpenAIRE |
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