Palliative treatment of patients with malignant structures of esophagus
| Autor: | Victor Ya. Zavodnov, Victor B. Loschenov, Kharnas Ss, Anna M. Posypanova, Alexander A. Stratonnikov, M. I. Kuzin, Kirill G. Linkov |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Lower esophagus medicine.diagnostic_test Palliative treatment business.industry medicine.medical_treatment Photodynamic therapy Esophageal cancer medicine.disease Dysphagia Endoscopy Surgery medicine.anatomical_structure medicine Photosensitizer Esophagus medicine.symptom business |
| Zdroj: | SPIE Proceedings. |
| ISSN: | 0277-786X |
| DOI: | 10.1117/12.230999 |
| Popis: | Photodynamic therapy with the use of laser endoscopic spectrum analyzer (LESA-5), spectral- analyzing video-imaging system, Kr laser and various types of catheters for different localizations and different geometry of tumor, and phthalocyanine aluminum photosensitizers in patients with malignant strictures of esophagus is discussed. Photodynamic therapy was carried out to four patients: with esophageal cancer (3 patients) and gastric cancer with infiltration of lower esophagus (1 patient). All patients suffered from severe dysphagia. Photosensitizer was used in a dose 1-1.5 mg/kg of weight. Usually we used 3-4 seances of laser treatment 10-30 minutes long. The accumulation of photosensitizer was controlled by LESA-5. Laser induced fluorescent image was monitored by the video-imaging system in order to control laser treatment. There were no side-effects. The results show high efficiency of photodynamic therapy. There was marked reduction of dysphagia symptoms in all cases. It seems that photodynamic therapy is a good alternative to palliative surgical treatment of patients with malignant strictures of esophagus.© (1996) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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