Surgical pathology of whipple pancreaticoduodenectomy: A 3-year experience at a tertiary cancer care center of marathwada region of India
| Autor: | Anagha S Varudkar, Rakesh Kumar J. Ajmera, Somesh Nilkanth, Hemant R. Kokandakar, Syeda Muneza, Ajay K. Boralkar |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Common bile duct business.industry Head of pancreas General surgery medicine.medical_treatment 030230 surgery Pancreaticoduodenectomy Whipple Procedure Surgical pathology 03 medical and health sciences Dissection 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Medicine Duodenal Carcinoma Radical surgery business |
| Zdroj: | IP Journal of Diagnostic Pathology and Oncology. 5:69-78 |
| ISSN: | 2581-3706 2581-3714 |
| Popis: | The aim was to study and analyze in detail various parameters of Whipple resection specimen. Introduction: Whipple procedure is a radical surgery performed for operable tumors of ampullaryperiampullary region, head of pancreas, common bile duct and duodenum. Pathologic assessment of Whipple’s resection specimen needs special attention because of peculiar complex anatomy of head of pancreas and related structures, and also because of difference of opinion about grossing protocols of dissection of the specimen and confusion about terms like ‘margins’ and ‘surfaces’ A histopathologist has to be aware of these intricacies so as to diagnose and accurately evaluate factors of prognostic importance. This is the first major mono-center surgical pathology study of Whipple resections reported from Department of Oncopathology, Government Cancer Hospital, Aurangabad, a newly started state level cancer hospital serving patients from Marathwada region of Maharashtra, India. Material and Methods: This is surgical pathology study of total 31(thirty one) cases of Whipple resections performed during 2017-19. All relevant histopathologic details pertaining to grossing, microscopic diagnosis, grading and staging, and histopathologic prognostic factors were comprehensively studied. Dissection and grossing was done as per the protocols followed at Tata Memorial Hospital Mumbai: Results: Out of total 31 Whipple resections performed at this hospital, 01(one) was classical Whipple’s PD, seventeen (17) were pylorus preserving pancreaticoduodenectomy(PPPD) andthirteen (13) were of extended pancreaticoduodenectomy resections. The patients had age ranging from 38 to 76 years. There were 20 male patients and 11 female patients (M:F- 2:1). As far as site of lesion is concerned 16(52%) cases had periampullary lesion. 06(19%)hadlesion in head of pancreas,07(22%) tumors were of common bile duct and there were 02(7%) cases of duodenal carcinoma. Histopathology revealed 29(94%) cases of ma |
| Databáze: | OpenAIRE |
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