Brain Magnetic Resonance Spectroscopy Findings in the Stroke-like Migraine Attacks after Radiation Therapy (SMART) Syndrome
| Autor: | Ana Ramos-González, Emilio Gómez-Cibeira, Elena Salvador-Alvarez, Juan Ruiz Morales, Patricia Calleja-Castaño, Fernando Sierra-Hidalgo, Jesús González de la Aleja |
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| Rok vydání: | 2015 |
| Předmět: |
In vivo magnetic resonance spectroscopy
medicine.medical_specialty business.industry medicine.medical_treatment Vasospasm Creatine medicine.disease Radiation therapy chemistry.chemical_compound Gliosis chemistry Migraine Anesthesia Internal medicine medicine Cardiology Choline Radiology Nuclear Medicine and imaging Neurology (clinical) medicine.symptom business Stroke |
| Zdroj: | Journal of Neuroimaging. 25:1056-1058 |
| ISSN: | 1051-2284 |
| DOI: | 10.1111/jon.12227 |
| Popis: | A 41-year-old male presented with an acute onset of headache, confusion, seizures, and unilateral focal neurological deficit 25 years after receiving whole-brain radiation therapy to treat a cerebellar medulloblastoma. Brain magnetic resonance imaging (MRI) demonstrated a thick unilateral parieto-occipital cortical contrast enhancement. A diagnosis of "Stroke-like Migraine Attacks after Radiation Therapy" (SMART) syndrome was made. Here, we describe the brain MR spectroscopy findings of SMART, showing a decrease in N-acetyl-aspartate and increased levels of creatine and choline, corresponding with neuronal destruction or transient neuronal impairment with mild nonspecific gliosis. The absence of a lactate peak suggests that mitochondrial dysfunction, vasospasm or ischemic mechanisms were not involved. |
| Databáze: | OpenAIRE |
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