Correlation between ANGPTL3 expression and tumor angiogenesis in hepatocellular carcinoma

Autor: China De-Yu Li, Zhengzhou, Hubei Province, Xiao-Ping Chen, Wuhan, De-Yu Li, Henan Province
Rok vydání: 2010
Předmět:
Zdroj: World Chinese Journal of Digestology. 18:3471
ISSN: 2219-2859
DOI: 10.11569/wcjd.v18.i32.3471
Popis: 目的:研究血管生成素样蛋白3(angiopoietin-like protein3,ANGPTL3)在肝细胞癌(hepato-cellular carcinoma,HCC)中的表达及其与血管生成的关系.方法:应用免疫组织化学方法检测96例肝癌组织和癌旁组织中ANGPTL3和VEGF的表达,同时检测其肝癌组织内微血管密度(microvessel density,MVD).应用Western blot方法检测肝癌组织和癌旁组织中ANGPTL3和VEGF的表达.结果:肝癌组织中ANGPTL3和VEGF表达与癌旁组织中比较显著增加(62.50%vs32.29%;81.25%vs29.17%,P
Databáze: OpenAIRE