Antioxidant activity of a halogenated monoterpene isolated from a Namibian marine algal Plocamium species
| Autor: | Christ W Shapumba, Petrina T. Kapewangolo, Michael G. Knott |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0106 biological sciences
0301 basic medicine Antioxidant biology DPPH 010604 marine biology & hydrobiology Monoterpene medicine.medical_treatment Red algae biology.organism_classification Ascorbic acid 01 natural sciences Absorbance 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology chemistry medicine Organic chemistry Hydrogen peroxide Food Science Plocamium |
| Zdroj: | Journal of Food Science and Technology. 54:3370-3373 |
| ISSN: | 0975-8402 0022-1155 |
| DOI: | 10.1007/s13197-017-2784-4 |
| Popis: | The antioxidant potential of various marine natural products is well documented. The aim of this study was to evaluate the antioxidant potential of a rare halogenated monoterpene, namely; 1E,3R,4S,5E,7Z-1-bromo-3,4,8-trichloro-7-(dichloromethyl)-3-methylocta-1,5,7-triene (1) for the first time. This compound was isolated from a Namibian red algal Plocamium species. The antioxidant activity of the compound was evaluated using a series of antioxidant assays, namely; 2,2-diphenyl-1-picryl-hydrazyl radical (DPPH), reducing power, nitric oxide (NO) and hydrogen peroxide (H2O2). The compound demonstrated remarkable DPPH, NO and H2O2 scavenging activities with IC50 values of 0.05 ± 0.01, 4.18 ± 0.22 and 5.58 ± 1.11 mM, respectively. The reducing power of the compound increased with an increase in concentration. These results were compared to the absorbance of ascorbic acid, which was used as a standard control in all the antioxidant assays. The results strongly suggest that compound 1 is a promising antioxidant agent with potential commercial applications. |
| Databáze: | OpenAIRE |
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