Will infant hepatitis B vaccination protect into adulthood? Extended Canadian experience after a 2, 4, 6 month immunization schedule

Autor: Pinto, Michelle, Dawar, Meena, Krajden, Mel, Naus, Monika, Scheifele, David W.
Jazyk: angličtina
Rok vydání: 2018
DOI: 10.14288/1.0357950
Popis: Introduction: Hepatitis B virus (HBV) vaccination programs generally target infants to prevent chronic HBV infection and/or pre-adolescents to reduce transmission in adulthood. To assess whether infant HBV immunization can potentially accomplish both objectives we measured residual immunity 10-16 years afterward in Canadian children. Methods: A prospective, parallel group, single center study enrolled adolescents given HBV vaccine at about 2, 4, 6 months of age. Exclusion criteria included prior HBV infection and additional vaccinations. At follow-up anti-HBs testing participants were 10-11 or 15-16 years old; those possibly lacking protection (
Databáze: OpenAIRE