Thrombocytosis
| Autor: | Jan Jacques Michiels, Craig M. Kessler |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Thrombocytosis Essential thrombocythemia business.industry Myeloid leukemia medicine.disease Gastroenterology Thrombosis Polycythemia vera Myeloproliferative Disorders medicine.anatomical_structure hemic and lymphatic diseases Internal medicine medicine Platelet Bone marrow business |
| Popis: | Thrombocytosis from excessive platelet counts is most commonly discovered on routine blood counts in asymptomatic patients. Most elevations are “reactive” due to enhanced physiological production of platelets from normal yet stimulated bone marrow function. This may result from many causes to include iron deficiency, inflammation, infection, or malignancy. This increase in platelet count is typically less than 1,000,000/mm3, not associated with thrombosis, and abates should the stimulation cease. A minority of cases are due to myeloproliferative disorders to include essential thrombocythemia, polycythemia vera, or chronic myeloid leukemia. These may result in thrombosis and, paradoxically, hemorrhage. Pathophysiology, diagnosis, prognosis, and therapy are discussed. |
| Databáze: | OpenAIRE |
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