Popis: |
In order to define interactions between external stimuli and physiological systems, the Frequency Tracking Locus (FTL) was devised which describes the cycle-by-cycle changes in phase angle and amplitude between two signals. The Path Length Index (PLI), describing the departure of the system from a fully entrained state, was derived from the FTL. The FTL was applied to the study of spontaneous respiration during mechanical inflation in newborn babies. Persistent states of 1:1 interaction and other integer ratio relationships were seen at different rates of mechanical ventilation. Stable states of entrainment corresponded to a PLI value of near unity, and the value of PLI increased rapidly as interactions became unstable. A bedside monitor incorporating the FTL has been successfully used as a clinical tool to aid mechanical ventilation of the newborn infant. > |