ChemInform Abstract: Interaction of Pentafluorobenzoylpyruvic Acid and Its Esters with N- Nucleophiles. Synthesis of 4-Oxoquinoline-2-carboxylic Acids

Autor:	Oleg N. Chupakhin, Z. E. Skryabina, P. N. Kondrat'ev, V. I. Saloutin, I. T. Basyl
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Ammonia Nucleophile Chemistry General Medicine Cyclohexylamine Medicinal chemistry Triethylamine Isopropyl
Zdroj:	ChemInform. 26
ISSN:	0931-7597
Popis:	Nitrogen-substituted 4-oxoquinoline-2-carboxylic acids have been prepared by the reaction of pentafluorobenzoylpyruvic acid with isopropyl-, cyclohexyl-, phenyl- and ethanol-amine. Ammonia and triethylamine, however, were found to react with pentafluorobenzoylpyruvic acid to form only the 2-carboxy-5,6,7-8-tetrafluorochromone; such behaviour has been found in the reactions of ethyl pentafluorobenzoylpyruvate with ammonia and cyclohexylamine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e6e4654cb165d4f8bd85fad9bab2bcc1 https://doi.org/10.1002/chin.199514166 Zobrazit plný text záznamu Plný text