Genomics and outbreaks: foot and mouth disease
| Autor: | Donald P. King, A Di Nardo, Graham L Freimanis, Jemma Wadsworth, D J King, K. Bankowska, Nick J. Knowles |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Foot-and-mouth disease viruses Genomic data Outbreak Genomics General Medicine Biology medicine.disease biology.organism_classification Disease control 03 medical and health sciences 030104 developmental biology Global distribution medicine Animal Science and Zoology Foot-and-mouth disease virus Environmental planning |
| Zdroj: | Revue Scientifique et Technique de l'OIE. 35:175-189 |
| ISSN: | 0253-1933 |
| DOI: | 10.20506/rst.35.1.2426 |
| Popis: | Foot and mouth disease virus (FMDV) is an animal pathogen of global economic significance. Identifying the sources of outbreaks plays an important role in disease control; however, this can be confounded by the ease with which FMDV can spread via movement of infected livestock and animal products, aerosols or fomites, e.g. contaminated persons and objects. As sequencing technologies have advanced, this review highlights the uses of viral genomic data in helping to understand the global distribution and transboundary movements of FMDV, and the role that these approaches have played in control and surveillance programmes. The recent application of next-generation sequencing platforms to address important epidemiological and evolutionary challenges is discussed with particular reference to the advent of 'omics' technologies. |
| Databáze: | OpenAIRE |
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