Local treatment of tendinopathies and myofascial painsyndromes with the 5‐HT3receptor antagonist tropisetron
| Autor: | W Müller, T Stratz |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
business.industry
medicine.drug_class Myofascial pain Immunology Analgesic General Medicine Pharmacology Myofascial pain syndrome Receptor antagonist medicine.disease Prilocaine 5-HT3 Receptor Antagonist Rheumatology Anesthesia Fibromyalgia medicine Immunology and Allergy Tropisetron business medicine.drug |
| Zdroj: | Scandinavian Journal of Rheumatology. 33:44-48 |
| ISSN: | 1502-7732 0300-9742 |
| DOI: | 10.1080/03009740410007032 |
| Popis: | The use of local tropisetron injections improved the treatment of tendinopathies considerably, with the effect being comparable to the topical application of local anaesthetics combined with depot corticosteroids. On the other hand, local injection of prilocaine alone exerted a shorter and weaker effect on the condition.Objectives: After it had been proven that systemic application of the 5‐HT3 receptor antagonist tropisetron exerts an analgesic effect on musculoskeletal pain in fibromyalgia, we investigated the efficacy of the substance in tendinopathies and myofascial pain syndromes.Results: Local injections of tropisetron as a treatment for trigger points in myofascial pain syndrome also brought about rapid and prolonged relief in the majority of cases. The analgesic effect was far superior to the action of local anaesthetics.Conclusion: The present findings indicate that the analgesic action of the 5‐HT3 receptor antagonist tropisetron sets in rapidly and lasts for a long time. Various mechanisms are ... |
| Databáze: | OpenAIRE |
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