SPECIFIC CHEMOTHERAPY DRUGS FOR DOGS WITH PYROPLASMOSIS TRANSMITTED BY IXODID TICKS

Autor: V. A. Levytska, Andrii Berezovskyi, A. B. Mushynskyi
Rok vydání: 2020
Předmět:
Zdroj: Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology. 21:26-32
ISSN: 2664-5610
2410-9029
Popis: Babesiosis is a natural focal seasonal diseases of carnivorous and farm animals. For treatment of this invasion is very important etiotropic therapy, as cases of self-healing of dogs are very rare. However, the use of only etiotropic drugs does not restore hematopoiesis, liver function and heart function. The experimental part of the work was carried out on the basis of the veterinary clinic "Fauna-Service" (Kamyanets-Podilsky) during 2019-2020. The study was performed on dogs of different breeds, genders and ages spontaneously affected by babesiosis. The diagnosis was established comprehensively, based on epizootiological data, clinical signs and laboratory results. It was identified specific clinical signs. The level of parasitaemia ranged from 1 to 3%. In the blood of dogs were recorded a decrease in erythrocytes, hemoglobin and lymphocytes relative to normal and an increase in such indicators as the number of leukocytes, alkaline phosphatase, ALT, AST, ESR, urea, creatinine, total bilirubin. According to the results of laboratory studies conducted 7 days after the start of treatment, it was found that in the second experimental group, where "Azidine-vet" was used three times and in combination with "Phos-Bevit" and "Carsilin" hematological and biochemical parameters of blood were normalized faster than with the first group in which "Azidine-vet" was used twice. Thus, the number of erythrocytes, hemoglobin and creatinine in the first group was 4.79 ± 0.41 1012 / l, 115.67 ± 12.23 g / l and 149.46 ± 17.65 mmol / l, and in the second – 5.35 ± 0.63 1012 / l, 143.12 ± 15.23 g / l and 111.67 ± 13.73 mmol / l, respectively. Both treatment regimens provided 100% efficacy in dogs with babesiosis. "Azidine-vet" when used three times in combination with an immunomodulator and hepatoprotector provides less toxic effects on the body of dogs and faster recovery of organ and system functions than the classic double use of the drug.
Databáze: OpenAIRE
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