Sudden death from idiopathic giant cell myocarditis

Autor: P. S. Khachatryan, K. A. Arsenyan, M. S. Bisharyan, A. A. Tonoyan
Rok vydání: 2021
Předmět:
Zdroj: Rechtsmedizin. 32:295-298
ISSN: 1434-5196
0937-9819
DOI: 10.1007/s00194-021-00539-9
Popis: Idiopathic giant cell myocarditis (GCM) is a rare rapidly progressing and usually fatal autoimmune disorder, which predominantly affects middle-aged people. It is usually associated with other autoimmune disorders, such as Crohn’s disease, rheumatoid arthritis, ulcerative colitis. We report an autopsy case of sudden death of a 38-year-old woman. At autopsy the heart was enlarged, with a motley appearance on sections. Microscopic examination showed abundant inflammatory infiltrates consisting of lymphocytes, leukocytes and multinucleated giant cells. Different staining methods and immunohistochemical examinations were performed for the diagnosis of GCM.
Databáze: OpenAIRE