Histaminergic Neurons in the Rat Brain after Acute Exposure to Alcohol

Autor:	E. M. Fedina, S. M. Zimatkin, V. B. Kuznetsova
Rok vydání:	2013
Předmět:	medicine.medical_specialty biology General Neuroscience Histaminergic Acid phosphatase Alcohol Dehydrogenase Metabolism chemistry.chemical_compound Endocrinology chemistry Anesthesia Lactate dehydrogenase Internal medicine Ultrastructure medicine biology.protein Monoamine oxidase B
Zdroj:	Neuroscience and Behavioral Physiology. 43:691-696
ISSN:	1573-899X 0097-0549
DOI:	10.1007/s11055-013-9794-0
Popis:	The aim of the present work was to study histaminergic neurons in the rat brain after single doses of alcohol. Experiments were performed on mongrel white male rats (n = 41) using histological, histochemical, morphometric, and electron microscope methods). At 1 h after alcohol at a dose of 4 g/kg, neurons became rounder and their cytoplasm showed decreases in NADH and glucose-6-phosphate dehydrogenase activities, along with increases in lactate dehydrogenase, monoamine oxidase B, and acid phosphatase activities; significant ultrastructural changes developed. At 6 h after alcohol, histaminergic neurons showed decreased signs of damage and increased structural-metabolic signs of adaptive changes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e5501f52ab99209fa16b7ddbb5044eda https://doi.org/10.1007/s11055-013-9794-0 Zobrazit plný text záznamu Full text from SpringerLink