Squamous cell carcinoma arising from a vulval epidermal cyst
| Autor: | Shirley Sze, Ian Richmond, Adam Bickers, Arabinda Saha |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty integumentary system medicine.diagnostic_test Epidermal Cyst Groin business.industry Obstetrics and Gynecology Histology medicine.disease Malignant transformation Vulva 030207 dermatology & venereal diseases 03 medical and health sciences Dissection 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Biopsy medicine Cyst business |
| Zdroj: | Journal of Obstetrics and Gynaecology Research. 42:1623-1626 |
| ISSN: | 1341-8076 |
| DOI: | 10.1111/jog.13091 |
| Popis: | Malignant transformation of epidermal cyst is rare, with most cases arising in the head and neck. Here, we report a case of squamous cell carcinoma arising from a longstanding epidermal cyst in the right vulva of a 65-year-old woman. The patient presented with a sudden increase in size of the cyst over 6 weeks to the size of a golf ball. Excisional biopsy and histology indicated moderately differentiated squamous cell carcinoma within an epidermal cyst (FIGO stage IB). Strong p16 immunopositivity was also demonstrated and the potential significance of this is discussed. Limited right hemivulvectomy and right groin node dissection were performed. |
| Databáze: | OpenAIRE |
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