| Autor: |
J. Stuart Woodhead, J.Paul Aston, Ian Weeks, Richard C. Brown |
| Rok vydání: |
1988 |
| Předmět: |
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| Zdroj: |
Clinical Applications of Monoclonal Antibodies ISBN: 9781461288619 |
| Popis: |
It is axiomatic that the key component of an immunoassay system is the antibody. Though other factors such as choice of label or method of separation may be important, it is the antibody which will ultimately determine the performance characteristics of the system. It is also generally accepted that if a monoclonal antibody can be readily produced to a required specification then it would invariably be used in preference to a polyclonal reagent. In reality the introduction of monoclonal antibodies into diagnostic immunoassay systems has been relatively slow, mainly for practical reasons. In this paper we shall consider the relative merits of monoclonal and polyclonal reagents within the context of the fundamental requirements for immunoassay design and optimization. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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