Functional MRI study on neural network dysfunction in schizophrenia and epileptic psychosis
| Autor: | Masato Taira, Takuya Kojima, Noriko Kanaka, Hiromi Ohkubo, Eisuke Matsushima, Masato Matsuura, Tatsunobu Ohkubo, Tetsuya Matsuda, Yasundo Nemoto, Mai Fukumoto |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
genetic structures
Artificial neural network medicine.diagnostic_test Neural substrate Eye movement General Medicine medicine.disease behavioral disciplines and activities Smooth pursuit Task (project management) Schizophrenia Saccade medicine Functional magnetic resonance imaging Psychology Neuroscience |
| Zdroj: | International Congress Series. 1270:311-314 |
| ISSN: | 0531-5131 |
| DOI: | 10.1016/j.ics.2004.05.047 |
| Popis: | To elucidate whether there is a common or a different neural substrate deficit between schizophrenia and epileptic psychosis, we have investigated brain activation patterns during various eye movement tasks using functional magnetic resonance imaging (fMRI). Compared with normal controls, low capacity or inefficiency in frontal function during visually guided saccade task and striate–thalamic hypo-function during anti-saccade task was found both in schizophrenia and epileptic psychosis. Therefore, these findings may not be attributable to disease but to a psychotic state. On the other hand, right hemisphere hypo-function during a smooth pursuit eye movement (SPEM) task with attention-enhanced procedure was found only in schizophrenia and may be a specific finding in schizophrenia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect