Infecciones en los niños quemados: análisis epidemiológico y de los factores de riesgo
| Autor: | Roberto Lede, María Teresa Rosanova, Daniel Stamboulian |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Body surface area
medicine.medical_specialty education.field_of_study business.industry medicine.medical_treatment Population Internal medicine Pediatrics Perinatology and Child Health Cohort Escharotomy Epidemiology medicine Antibiotic prophylaxis Risk assessment education business Prospective cohort study |
| Zdroj: | Archivos Argentinos de Pediatria. 111:303-308 |
| ISSN: | 0325-0075 |
| DOI: | 10.5546/aap.2013.303 |
| Popis: | Introduction Burns are the third cause of accidental deaths among children. Approximately 50-60% of these deaths are the result of an infection. Objective To determine infection related risk factors in burned children. Population and methods All patients admitted to the Burn Unit of Hospital "Prof. Dr. Juan P. Garrahan" between June 2007 and December 2009 were included. The epidemiology of hospital-acquired infections and the associated outcome measures were determined. Groups of infected and non-infected children were compared using Student's t test or the Mann-Whitney Rank Sum test, as applicable. Dichotomous outcome measures were analyzed with the X2 test using Yates' correction. In order to assess the predictive value of independent outcome measures, the multiple logistic regression model was applied. Results In this cohort of 110 children, 128 hospital-acquired infections were recorded in 84 patients. There were 17 deaths (15%); 14 out of these 17 (82%) were related to infection. Infection-related factors included the percentage of burned body surface area; the highest Garces' index; burn depth; antibiotic prophylaxis; the use of topical antibiotics; the presence of a central venous line, an arterial line, a urinary catheter, mechanical ventilation support, escharotomy, and the need of a graft. The multivariate analysis showed a higher risk of infection with the use of central venous lines (RR: 5.15; 95% CI: 1.44-18.46), antibiotic prophylaxis (RR: 5.22; 95% CI: 1.26-21.63), and graft requirement (RR: 3.65; 95% CI: 1.08-12.37). Conclusions The presence of lines or catheters, antibiotic prophylaxis, and graft requirement were independent risk factors for infection in burned children. |
| Databáze: | OpenAIRE |
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