Towards nucleopeptides containing any trifunctional amino acid (II)

Autor:	Maite Beltrán, Yolanda Pérez, Vicente Marchán, Anna Grandas, Enrique Pedroso, Jordi Robles, Isaura Travesset
Rok vydání:	2002
Předmět:	chemistry.chemical_classification Arginine Amino acid composition Chemistry fungi Organic Chemistry Drug Discovery food and beverages Organic chemistry Asparagine Biochemistry Cysteine Amino acid
Zdroj:	Tetrahedron. 58:6965-6978
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(02)00793-7
Popis:	Nucleopeptides with no restriction in the amino acid composition can be synthesized using stepwise solid-phase methodology. Best conditions for the protection of arginine and cysteine, as well as for the final deprotection treatment are established, and our conclusions can be extended to the preparation of any peptide–oligonucleotide hybrid. The association between certain side reactions and nucleopeptide sequences is also discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e3f825a4b81bb47d44e0a06894faaefc https://doi.org/10.1016/s0040-4020(02)00793-7 Zobrazit plný text záznamu Full Text from ScienceDirect