Fluorescence tomography in turbid media based on acousto-optic modulation imaging

Autor:	Masaru Enomoto, Yukihiro Shibuya, Masaki Kobayashi, Takashi Mizumoto, Motohiro Takeda
Rok vydání:	2006
Předmět:	Tomographic reconstruction Materials science Physics and Astronomy (miscellaneous) business.industry Scattering Physics::Medical Physics Ultrasound Fluorescence Light scattering Optics Modulation Ultrasonic sensor business Refractive index
Zdroj:	Applied Physics Letters. 89:181102
ISSN:	1077-3118 0003-6951
DOI:	10.1063/1.2364600
Popis:	The authors present a tomographic imaging technique of fluorescence in light-scattering media. Ultrasonic modulation of fluorescence based on the interaction between ultrasound and light is applied for imaging of a fluorescent material by scanning a focused sound field in which the light is modulated selectively. The on-axis sound-field characteristics that affect the light by modulating its amplitude (through variation of the refractive index and the scattering coefficient) were determined. That imaging technique is demonstrated using tissue phantoms that contain localized fluorescent regions in a dense scattering medium, suggesting the applicability of this technique for visualization of fluorescent probes in biological tissues.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e12da9fb28e8b39ad38427f1358a5083 https://doi.org/10.1063/1.2364600 Zobrazit plný text záznamu