Moderately Increased Albuminuria; Marker of Chronic Complications in Nigerian Diabetes Mellitus Type 2 Patients; Makurdi Perspective
| Autor: | Christian Ejike Onah, C. E. Dioka, S A Adebisi, B K Myke-Mbata, E K Oghagbon, G I Achinge, B O Onyemailo, Samuel C. Meludu |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Environmental Engineering endocrine system diseases business.industry Type 2 Diabetes Mellitus Type 2 diabetes medicine.disease Diabetic foot Industrial and Manufacturing Engineering Nephropathy Surgery Coronary artery disease Internal medicine Diabetes mellitus medicine Albuminuria Microalbuminuria medicine.symptom business |
| Zdroj: | British Journal of Medicine and Medical Research. 9:1-6 |
| ISSN: | 2231-0614 |
| DOI: | 10.9734/bjmmr/2015/18128 |
| Popis: | Background: Diabetes mellitus (DM) and its complications are on the increase especially in the developing countries with significant negative economic consequences on individuals, families and health systems.Objective: We, therefore compared albumin/creatinine ratio, microalbuminuria, and HbA1c among subjects of varying degree of complications with controls to ascertain if they can serve as markers of diabetic chronic complications to enhance early detection of chronic complications amongst diabetes mellitus patients in developing countries.Methods: 109 type 2 DM subjects (47 males and 62 females) and 100 non-DM controls of the same age range (40-80 yrs) were recruited for this study. The chronic complications found were: nephropathy, retinopathy, coronary artery disease, cerebrovascular disease, peripheral vascular disease and diabetic foot. These were further classified into micro vascular complications (nephropathy and retinopathy) and macrovascular complications (Coronary Artery Disease, Cerebrovascular Disease, Peripheral Vascular Disease and diabetic foot).Out of these 109 DM subjects, 36 were without chronic complications, 37 have microvascular complications only and 36 have a combination of microvascular and macrovascular complications. HbA1c, Urine microalbumin and creatinine were analysed using standard methods.Results: The mean levels of HbA1c, Microalbuminuria and albumin-creatinine ratio were significantly higher in DM subjects when compared to the control (p |
| Databáze: | OpenAIRE |
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