Comparison of antibacterial and toxic effects of various root canal irrigants
Autor: | Osman Zekioglu, S. Hilmioğlu, D. Burhanoğlu, Cemal Eronat, Ozant Oncag, M. Hoşgör |
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Rok vydání: | 2003 |
Předmět: |
Microbiological culture
Materials science biology Cetrimide Bacterial growth biology.organism_classification Enterococcus faecalis Microbiology chemistry.chemical_compound medicine.anatomical_structure chemistry Sodium hypochlorite Toxicity Deciduous teeth medicine Anaerobic bacteria General Dentistry |
Zdroj: | International Endodontic Journal. 36:423-432 |
ISSN: | 0143-2885 |
Popis: | Aim To compare the antibacterial properties and toxicity of 5.25% sodium hypochlorite (NaOCl), 2% chlorhexidine gluconate and 0.2% chlorhexidine gluconate plus 0.2% cetrimide (Cetrexidin®; Vebas, San Giuliano, Milan, Italy). Methodology The antibacterial effects of the irrigants in vitro were examined after 5 min and 48 h in freshly extracted human teeth with single roots, whose canals were infected by Enterococcus faecalis ATCC 29212. In a separate in vivo study, bacterial culture samples were collected before treatment from the infected root canals of deciduous teeth containing necrotic pulp tissue. Irrigants were used to clean the canals which were then left empty for 48 h. Aerobic/facultative anaerobic and anaerobic bacterial growth were compared before and 48 h after irrigation. Finally, the toxic effects of the irrigants were assessed by injecting them into the subcutaneous tissues of rats. The inflammatory reactions that occurred 2 h, 48 h and 2 weeks after the injections were evaluated. Results In the laboratory study, the 2% chlorhexidine gluconate and Cetrexidin® were significantly more effective on E. faecalis than the 5.25% NaOCl at 5 min (P |
Databáze: | OpenAIRE |
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