| Autor: |
Dalibor Matysek, Marek Piątkowski, Oleksandr Oleshko, Viktoriia Mykolaivna Holubnycha, Viktoriia Korniienko, Łukasz Janus, Ye. Husak, Maksym Pogorielov, Volodymyr Deineka, Julia Radwan-Pragłowska |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Springer Proceedings in Physics ISBN: 9789811539954 |
| DOI: |
10.1007/978-981-15-3996-1_10 |
| Popis: |
Local hemostatic agents are a necessary element of surgical work that reduces blood loss and mortality. Despite the variety of materials, there is no perfect styptic. The most promising hemostatic agents are based on biomaterials therefore they can be left in the wound. The aim of the following research was to obtain a new type of biocompatible chitosan-based agents with high hemostatic activity. The biomaterials were obtained under microwave radiation using l-aspartic acid, l-glutamic acid as crosslinking agents. Chitosan sponges showed high porosity and antioxidant activity, and also high antibacterial activity against both S. aureus and to E. coli. This material was absolutely non-toxic on cell culture and showed good hemostatic properties after interaction with blood in vitro. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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