Factors associated with human papillomavirus infection – findings from a cervical cancer screening program for female employees in Beijing
| Autor: | Hong Yu, Wei-hua Lv, Yu Zhong, Hui-xia Yang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Cervical cancer medicine.medical_specialty Hpv genotyping business.industry HPV infection virus diseases medicine.disease Logistic regression Cervical cancer screening 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Oncology Beijing 030220 oncology & carcinogenesis Internal medicine medicine Binary logistic regression analysis Human papillomavirus business |
| Zdroj: | Cancer Management and Research. 11:8033-8041 |
| ISSN: | 1179-1322 |
| DOI: | 10.2147/cmar.s209322 |
| Popis: | Background In 2018, the Beijing Federation of Trade Unions organized a cervical cancer screening program for female employees for the first time. This study aimed to investigate the screening results of this program and determine the factors associated with human papillomavirus (HPV) infection. Methods A total of 8297 female employees participating in the screening program between January 1, 2018, and December 31, 2018, were enrolled in this study. The methods for screening cervical cancer included ThinPrep cytology test (TCT) and HPV genotyping test. Single-factor analysis and multiple binary logistic regression analysis were used to identify the factors associated with HPV infection. Results Of the 8297 women (median age: 43.00 years), TCT was found to be abnormal in 116 patients (1.40%) and 1169 (14.09%) were positive for HPV genotyping test. Notably, HPV-52 was the most prevalent subtype (3.05%), followed by HPV-16 (2.82%), HPV-58 (2.01%), HPV-51 (1.58%) and HPV-56 (1.49%). Multivariate logistic regression analysis revealed that taxi drivers (OR =1.98; 95% CI =1.31-2.99) and single women with a history of sexual activity (OR =2.32; 95% CI =1.41-3.82) were significantly associated with an increased risk of HPV infection (P |
| Databáze: | OpenAIRE |
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