Nickel-Catalyzed Asymmetric Hydrogenation for Kinetic Resolution of [2.2]Paracyclophane-Derived Cyclic N-Sulfonylimines

Autor:	Yong-Gui Zhou, Yang Zhao, Yi-Xuan Ding, Bo Wu
Rok vydání:	2021
Předmět:	Nickel chemistry Organic Chemistry Asymmetric hydrogenation High selectivity chemistry.chemical_element Combinatorial chemistry Kinetic resolution Catalysis
Zdroj:	The Journal of Organic Chemistry. 86:10788-10798
ISSN:	1520-6904 0022-3263
Popis:	Nickel-catalyzed asymmetric hydrogenation for kinetic resolution of [2.2]paracyclophane-derived cyclic N-sulfonylimines was successfully developed. High selectivity factors were observed in most cases (s up to 89), providing the recovered materials and hydrogenation products in good yields with high levels of enantiopurity. The recovered materials and hydrogenation products are useful synthetic intermediates for the synthesis of planar chiral [2.2]paracyclophane-based compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ddcc091402060987e9edf24d0e0bc2e5 https://doi.org/10.1021/acs.joc.1c01011 Zobrazit plný text záznamu