Association of Non -Alcoholic Fatty Liver Disease in Diabetes Mellitus-Chronic Kidney Disease Patients

Autor: Rahman MM, Dutta R, Patwary RI, Ahmad HI, Imam I, Akhtar K, Islam F, Hamid MA, Ghose A
Rok vydání: 2022
Předmět:
Zdroj: Scholars Journal of Applied Medical Sciences. 10:493-499
ISSN: 2320-6691
2347-954X
Popis: Introduction: Non-Alcoholic Fatty Liver Disease (NAFLD) is now the most common chronic liver condition in the world, affecting up to 9% of people in the developing and up to 30% in the developed world. The aim of the study was to find out the association of Non-Alcoholic Fatty Liver Disease with Diabetes Mellitus-chronic kidney disease (DM-CKD). The aim of the study was to find out the association of Non-Alcoholic Fatty Liver Disease with Diabetes Mellitus-chronic kidney disease (DM-CKD). Methods: This cross-sectional observational study was carried out at the Nephrology department of Chittagong Medical College Hospital, Chittagong for 6 months, where 50 patients of DM-CKD were enrolled. Data was collected by pretested questionnaire through face-to-face interview from those patients who gave consent and fulfilled inclusion criteria. Result: Most of the respondents were male 64% and from upper middle class 48%. Among the respondents 34% had non-alcoholic fatty liver disease. Triglyceride level in presence of NAFLD was more (NAFLD pr.=335.12, SD=158.98) vs NAFLD absent (NAFLD ab.=169.64, SD=35.84) and mean LDL level of the patients without NAFLD was more (NAFLD ab.= 124.76 SD=39.24) vs with NAFLD (NAFLD pr.=71.82, SD= 37.16). Mean LDL level of the patients in absence of NAFLD is more (NAFLD ab.= 124.76, SD=39.24) than those NAFLD present (NAFLD pr.=71.82, SD= 37.16). In this study we found a significant relation between Serum Cretinine level and NAFLD (p=0.022). We also found a higher RBS level in patients with NAFLD t (50) =3.699, p= 0.001. Conclusion: The study found that among DM-CKD patients with NAFLD male from upper middle socio-economic class are more likely to develop the disease. That indicates poor renal function and progression to end stage renal disease is more likely in those patients. Early treatment and strict control of risk factors as well as special attention may halt disease progression in these patients.
Databáze: OpenAIRE
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