Interaction of richlocain with some linear and crosslinked polymers

Autor:	Larisa A. Bimendina, G. Sh. Makysh, Sarkyt E. Kudaibergenov
Rok vydání:	2002
Předmět:	Polymers and Plastics Sodium polyacrylate Organic Chemistry Polyacrylic acid Polyelectrolyte Solvent chemistry.chemical_compound chemistry Ionic strength Polymer chemistry Materials Chemistry Copolymer Solvent effects Drug carrier
Zdroj:	Polymer. 43:4349-4353
ISSN:	0032-3861
DOI:	10.1016/s0032-3861(02)00268-9
Popis:	The interaction of local anesthetic drug richlocain with linear polyacrylic acid and crosslinked sodium polyacrylate, linear and crosslinked acrylic acid–Schiff base copolymers has been investigated. The compositions of forming polymer–drug complexes were determined. The influence of external factors such as pH, ionic strength, temperature and thermodynamic quality of solvent on the stability of these complexes was studied. The kinetics and activation energy of drug release from the gel matrix has been evaluated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::daf322f7db1ac09bf0ac68125453e3d7 https://doi.org/10.1016/s0032-3861(02)00268-9 Zobrazit plný text záznamu Full Text from ScienceDirect