Acute temporal effect of ambient air pollution on common congenital cardiovascular defects and cleft palate: a case-crossover study

Autor: Temuulen Enebish, Meredith Franklin, Rima Habre, Carrie Breton, Nomindelger Tuvshindorj, Gantuya Tumur, Bayalag Munkhuu, David Warburton
Rok vydání: 2022
DOI: 10.1101/2022.03.06.22271984
Popis: This symmetric bidirectional case-crossover study examined the association between short-term ambient air pollution exposure during weeks 3-8 of pregnancy and certain common congenital anomalies in Ulaanbaatar, Mongolia, between 2014 and 2018. Using predictions from a Random Forest regression model, authors assigned daily ambient air pollution exposure of particulate matter 2.5 (OR: 2.25, 95% CI: 0.62-8.1), SO2 (OR: 2.6, 95% CI: 0.61-11.12), and CO (OR: 2.83, 95% CI: 0.92-8.72) in week 4. Our findings contribute to the limited body of evidence regarding the acute effect of ambient air pollution exposure on common adverse birth outcomes.
Databáze: OpenAIRE