Lipid peroxidation in all-in-one admixtures for preterm neonates: impact of amount of lipid, type of lipid emulsion and delivery condition

Autor:	Eric Barbotte, Anaïs Grand, Anne Jalabert, Jean-Paul Steghens, Christelle Pigue, Jean-Charles Picaud
Rok vydání:	2011
Předmět:	business.industry General Medicine Lipid peroxidation chemistry.chemical_compound Parenteral nutrition Biochemistry chemistry Pediatrics Perinatology and Child Health Lipid emulsion Medicine Composition (visual arts) Food science business Light exposure
Zdroj:	Acta Paediatrica. 100:1200-1205
ISSN:	0803-5253
DOI:	10.1111/j.1651-2227.2011.02269.x
Popis:	Aim: To evaluate the effect of lipid emulsion composition and delivery condition on lipid peroxidation in typical all-in-one parenteral admixtures for preterm neonates. Methods: Malonedialdehyde (MDA) concentrations were assessed in different all-in-one admixtures. We evaluated the effects of fat blend (three lipid emulsions) and the amount of lipids, as well as the effects of protecting bags and/or tubing from ambient light and storage for 72 h. MDA was measured by liquid chromatography/mass spectrometry. Results: Three hundred and sixty samples were collected from 114 admixtures. Neither the type of lipid (p = 0.43) nor the interaction between light and type of lipid (p = 0.49) had any influence on final MDA concentrations, but the increase in MDA concentration at 24 h (T24) was related to light exposure (p
Databáze:	OpenAIRE
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